I finally came up on the best excuse to upgrade my computer. My very generous employer, ITQ, gave us the opportunity to upgrade our home office and that brought me the base for a new system.
The specs I finally settled on are built around PCI Gen 4 (future-proof a bit 😀) support which comes down to the following list of parts:
Asus TUF Gaming X570-Plus AMD Ryzen 7 5800X Samsung 980 Pro 500GB 32GB G.